Some other research discovered that enhanced serotonin metabolism may also contribute to decreased central serotonin levels following gut dysbiosis (173)
as an anti-ferroptotic factor that parallels the GSH system [82, 83]
With the increased detoxification requirement of the liver, more selenium is then utilised to produce more glutathione, resulting in a deficiency
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Notably, a study involving approximately 276,000 participants from the UK Biobank cohort revealed that permanent night shift work, a condition acknowledged to reduce 24-hour melatonin levels [41], was associated with a 1.5-fold higher risk of developing AD during a median follow-up of 9 years [42]
So which number is correct